Friday, May 28
2:00-4:00 PM SLTBR Board Meeting
7:00-9:00 PM Welcome
Reception and Poster Session I:
Chronophysiology, Medical Chronobiology, and Chronotherapeutics and Seasonal Affective Disorder, Light
Therapy, and Melatonin
Saturday, May 29
7:30-8:45 AM Registration,
Continental Breakfast, Corporate Exhibits
8:45- 9:00 AM Welcome: Anthony Levitt
MD, President, SLTBR and Erhard Haus MD, PhD, President, AAMCC
9:00-11:30 AM Plenary Session I:
Overview: Epidemiological studies indicate a very strong association between cardiovascular diseases and depression, although more work is needed to delineate the specific mechanisms involved. In this session, a brief case report will introduce and highlight several chronobiological issues that may contribute to the overlap of cardiovascular disease and mood disorders. Various models of pathology will be considered, covering biological rhythms, social rhythms, and administration-time-dependent side effects of medications.. The role of targeted treatment strategies based on novel chronotherapeutic approaches also will be considered.
Session Topics:
2. The Chronobiology of Depression
3. Blood Pressure Circadian Rhythms in Hypertension and Their Etiology
4. The Chronobiology of Cardiovascular Disease
5. Current and Future potential Chronotherapies of Hypertension and Ischemic Heart Disease (20 Minutes)
Discussion:
Chronobiology at the interface of medical/psychiatric co-morbidity: pathophysiology
and treatment issues.
11:30 AM - 12 PM SLTBR Junior Investigator Award and Research Presentation
12 PM- 1:30 PM Lunch
1:30 PM- 3:30 PM Oral Presentations: Seasonal Affective Disorder, Light Therapy, and Melatonin
3:30 PM - 4:30 PM SLTBR Business meeting (all invited)
4:30 PM – 6:00 PM Poster
Session II:
Chronobiology and chronotherapy
of Depression, Hypertension, Cardiovascular Disease, Appetite, Food
Consumption, and Physical Activity, and
Seasonal Affective Disorder, Light Therapy, and Melatonin
7:00 PM – 10:00 PM Reception and Banquet
Sunday,
May 30
Chronobiological Issues in the Pathophysiology of Appetite Regulation
and Management of Obesity and Eating Disorders
Overview: It is well established that obesity is increasing at epidemic rates around the world, with enormous costs in terms of decreased quality of life, long-term morbidity and mortality, and financial strain to health care systems. Current approaches to obesity may be limited in their relative lack of consideration of chronobiological and chronobehavioral factors related to eating behavior, nutrient selection and physical activity. In this session a number of chronobiological issues in the etiology and management of obesity will be considered, including circadian, circamensual, and circannual rhythms of eating behavior and body weight regulation on the one hand, and altered activity rhythms on the other. Understanding how modern environmental and societal factors might disrupt normal rhythms of eating and activity to produce obesity will be considered. The session will end with a group discussion of how the field of chronobiology can contribute to the understanding, prevention, and treatment of this major health problem.
1. Introduction to Eating Disorders
2. Epidemiology of Obesity in Children and Adults
3. Chronobiologic Regulation of Appetite and Feeding: Pre-clinical and Human Models
4. Normal and Abnormal Nocturnal, Menstrual Cycle and Seasonal Human Eating Behaviors
5. Progress in the (Chrono)pharmacotherapy of Obesity
Discussion: Contribution of the field of Chronobiology to the understanding, prevention, and treatment of obesity and eating disorders
10:30 AM- 12:00 PM Oral Presentations: Seasonal Affective Disorder, Light Therapy,
Melatonin, and Chronotherapeutics
12:00
PM- 12:15 PM Closing
Remarks
1:30 PM – 5:00 PM CME Course:
I. Light
Therapy for SAD
Learning objectives:
A. To identify patients most likely to respond to light treatment.
B. To learn a standardized protocol for light treatment in SAD patients.
C. To become familiar with the different light units available.
D. To consider safety issues with various light treatments.
II.
Non-light treatments for SAD
Learning
objectives:
A.
To review response rates for light therapy in SAD.
B.
To review studies comparing light therapy and medication.
C.
To learn about which medicines have been shown to work for SAD.
D.
To learn about other alternative approaches to SAD.
Learning objectives:
A. To learn about rhythm-disturbances as causal of functional and organic disorders
B. To review rhythms in human disease and their symptoms
C. To discuss biological rhythm-dependencies of common diagnostic tests.
Learning objectives:
A. To review concepts and mechanisms of chronopharmacology (administration-time
differences in the pharamcokinetics and effects) of medications.
B. To present examples of
chronopharmacokinetics and chronodynamics.
C. To discuss the rationale for the chronotherapy of medications.
D. To review current chronotherapies in clinical use today.